Dr. Lu's career trajectory and multi-disciplinary experience have cultivated her long-standing research interest, in understanding how the conformational dynamics of proteins govern the equilibrium of distinct static structures to execute their biological functions in infectious diseases. She has diverse education and training background in biomedical research, including biophysics, virology, biochemistry, and molecular biology. During her graduate study, she was trained as a biophysicist (primarily dry-lab instrumentation and mathematical analysis) in single-molecule technologies, especially single-molecule FRET (smFRET) imaging of proteins. She chose virology for her postdoc training, where she applied her single-molecule imaging toolbox to a brand-new field (extensive wet-lab experiments). She became fascinated by the infection lifecycle of retroviruses, soon mastered the necessary virology toolbox, and managed to offer her dynamics perspective on the entry mechanisms of retrovirus. She believes that combining different ideas and expertise is most powerful in tackling challenging scientific questions in disease-determining biological processes. Thus, she strives to continue learning new technologies and has continuously established collaborations with multiple research groups in structural biology, virology, biophysics, and computational biology.
Xi'an Jiaotong University, Xi'an, China - MS, BS
Bowling Green State University, Bowling Green, OH - PhD
Yale School of Medicine, New Haven, CT - Postdoctoral